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It contains the oligonucleotide/oligosaccharide-binding fold which is found in all three kingdoms and its common architecture presents a binding face that has adapted to bind nucleic acids including the anti-codon binding domain of lysyl, aspartyl, and asparaginyl-tRNA synthetase [59].
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Find a face that has your FC.
The principal sites of interaction in the endothelin ligand all lie on one face of a helix that has been implicated by structure-activity relationship studies as being essential for binding.
The ECHR's judgments are binding on countries that have ratified the European Convention on Human Rights.
In addition to the distal and proximal faces, the torus-shaped Hfq hexamer bears a convex circumferential rim that has recently been identified as a surface contributing to RNA binding (Sauer et al., 2012; Zhang et al., 2013).
Another May idea that has been broadly welcomed is making shareholder votes on corporate pay not just advisory but binding.
The approach that has been adopted and implemented in 'Auto-FACE' is suitable for simple to complex protein-ligand interactions, particularly mechanisms that involve allosteric structural changes in addition to binding process.
She is visiting the Bölls when Sophie dies, lying in bed alongside her husband: "He cried into her skin and into the darkness that was quickly replacing the fading light that had been her face and suddenly, like the escape of some binding secret held within us the entire length of our lives, he felt a slight, then brutal, shift.
Strikingly, the exposed face of H1 contains residues Trp57 and Leu58 that have been implicated in direct binding to CD4 (Grzesiek et al., 1996a; Figure 7D).
Usually, the support groups that have been studied have been face-to-face ones.
Interventions that had additional treatment arms such as face-to-face sessions were also included.
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