Sentence examples for binding experiments have shown from inspiring English sources

Furthermore, competition binding experiments have shown that resveratrol was the most potent competitor in HaCaT cells withµmolar affinity (resveratrol > piceatannol > EGCG) (data not shown).

Furthermore, competition binding experiments have shown that resveratrol was able to inhibit specific [3H]-resveratrol binding sites in the epidermal and dermal layers with Ki values of 2.6 and 1.5 µM, respectively, which are highly similar to low affinity sites observed in brain homogenates (present data manuscript; see also [21].

In vitro RNA - protein binding experiments have shown that QC inhibited the binding of p33 replication protein to the internal replication element [p33RE consisting of the stem-loop RII-SL] required for recruitment of the TBSV RNA into replication [11], [13].

Computational modeling and DNA binding experiments have shown that the GT dinucleotide, which is common to both the ETS and CRE motifs, is bound by the CREB1 dimer in the major groove, and that GABPα binds in the minor groove, without protein protein interactions between the two proteins (Chatterjee et al. 2011).

Recently, protein binding microarray experiments have shown that the sequence variety and position-interdependence between bases in sequence motifs are even higher than previously expected, and that TFs bind a rich spectrum of k-mers not fully captured even by multiple PWMs [7].

In contrast to such experiments showing that relatively minor sequence changes may affect IgE binding other experiments have shown that four of 6 Bet v 1 orthologous allergens and proteins with >60% identity in related species are cross reactive.

Peptide binding and dissociation experiments have shown that peptide-free MHC II can adopt two interconverting forms, one receptive to and one averse to peptide loading [11], [12], [13].

Although the results in Figure 5b show that Lys211 and Lys214 enable TRBP-RBD2 to recognize and bind to dsRNA, experiments have shown that single mutations of His188, Lys210, and Lys214 block TRBP-RBD2 binding to dsRNA.

Equilibrium dialysis experiments have shown that GTP binding is not dependent on SAM binding, and that the position 6 oxo group and the amino group at position 2 are important for guanine recognition by MoaA.

It is also possible that mPPARα and hPPARα preferentially bind different degenerate PPRE sequences, as previous experiments have shown species variation in rodent and human PPRE sequence binding.

Recently, in-line probing experiments have shown that the leader linker interaction increases glycine binding affinity and removes the previously accepted cooperativity between the two glycine binding sites.