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This model allowed us to estimate the specificity of ChIP-based TF-DNA binding events for several TFs.
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Thus, it is clear that there are separate binding events for oxysterols and these other compounds.
For example, no significant liver disease ontology enrichments were found for shared singleton CEBPA binding events; however, several cancer disease enrichments from various tissues, such as in situ carcinoma (q = 1.91 × 10−5), were obtained.
Binding events were identified for NANOG at the same genomic position but not for SOX2.
Computational molecular dynamics enables atomic level resolution of the interaction between albumin and atRA during several binding events.
Consensus binding sites for several other factors were also identified.
Data on genomic binding sites for several factors were obtained from several sources.
In addition to the binding site for STAT3, the VEGF gene promoter contains binding sites for several potential transcription factors.
Each event can be characterized by one or more trigger words, such as 'heterodimerization' or 'binding partner' for binding events.
Preliminary results demonstrate how this system can be used to monitor several independent biospecific binding events simultaneously.
Thus, for such binding events to occur, separation of the two EDs would be required.
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CEO of Professional Science Editing for Scientists @ prosciediting.com