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There was significant enrichment in genes containing binding elements for the transcription factor NF-Y (p = 4.79E-19, 40/75 genes, Table 4, underlined).
Binding elements for the nuclear transcriptional regulatory factors, NF-κB, CCAAT/enhancer binding protein beta, Sp-1, AP-1 and CREB are present in the promoter regions of numerous cytokine genes, including those whose expression is increased after blood loss.
The scope of this work was to employ an ab initio motif detection approach, coupled with gene ontology analysis, in order to define novel binding elements for the bacterial transcription factor AtoC.
In silico analyses identified putative binding elements for the defence-induced ERF, Myc2, TGA and WRKY transcription factors in the promoters of four out of the six defence-related maize NAC transcription factors, while one of the analysed maize NAC did not contain any of these potential binding sites.
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"The most binding element for the Indian diaspora is no longer just Bollywood or cricket.
Since the minimal Epo promoter contains an E-box motif, which could represent a binding element for the transcription factor heterodimer CLOCK∶BMAL1 as the major circadian regulator, we tested herein the hypothesis that these factors could be involved in diurnal oscillation of Epo mRNA expression.
The binding element for the Smad 2 and 3 transcription factors can be used to monitor smad2/3 gene activation.
Based on these results we propose that SPM co-operates with CM1 to form a bipartite binding element for the γ-TuSC.
We previously found that inhibition of the SIKs in primary macrophages not only induces IL-10 mRNA synthesis but also that of many other genes which all have in common a binding element for the transcription factor CREB within their promoter [ 13].
And, GT is also a key binding element for these two models towards developing the integrated approach.
Such regions are usually enriched in regulatory cis-acting binding elements for transcription factors that exclude the positioning of nucleosomes and could thus indirectly affect the organization of chromatin.
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