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However, T-box and Smad binding elements do not form part of the same motif, and although they appear in close proximity to each other they have inconsistent spacing, orientation and strand orientation relative to each other.
Similar(58)
While the presence of a binding element does not confer regulation, MSI1 regulation of lipid metabolism may be more complex than simple direct regulation of SCD.
A luciferase reporter assay after transfection of the cell lines with a luciferase expression construct under the control of a promoter harbouring tandem β-catenin-binding elements did not show significant differences in luciferase activity either (Fig 4A).
Antinerd elements do not make life miserable.
These elements do not facilitate social cohesion.
6-CN-PiB did not label dystrophic neurites, indicating that plaque-associated neuritic elements do not likely contribute to overall PiB signal, despite the robust labelling of these structures with other amyloid-binding compounds such as X-34.
It would also be helpful to add an additional overlay structure to the figure that shows that these elements don't change upon C-tail binding.
Its elements don't fuse.
Other elements don't work so well.
Our data suggest that deletion of the ORC binding site of the silencer element does not completely abrogate a role of Fun30 in silencing within the HMR.
They found that the binding affinity between GR and its response element did not correlate with transcriptional activity.
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