Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
In order to confirm that the RBE and hairpin arms played no role in Rep specificity, we generated a chimeric ITR with ITR5 binding elements and an ITR2 spacer and nicking stem (ITR5+2SNS).
Similar(59)
The 3xP3 promoter consists of three P3 binding elements and a minimal promoter from the Drosophila hsp70 gene.
The duplicated region contains three NOBOX-binding elements and an E-box, important for GDF9 gene regulation.
Among these CNVs, a tandem duplication of 475 bp containing 3 NOBOX-binding elements and an E-box important for GDF9 gene regulation in the promoter of GDF9 is likely causative of POI (Norling et al., 2014).
An analogous origin (AAV5) possesses a unique interaction between an extended Rep binding element and a 49 aa region of Rep containing two DNA binding interfaces.
It has been reported that CAGA is a Smad binding element and a promoter assay vector containing tandem repeats of CAGA in the minimum promoter region ((caga 12-MLP-Luc) is a sensitive and specaga 12-MLP-Lucorter vecaga 12-MLP-Luc.
The corresponding chimeric ITR (ITR2 binding elements and spacer with an ITR5 nicking stem) was replicated by both Rep2 and Rep5 (ITR2+5NS, Fig. 1B).
The d.n.FoxO therefore acts through outcompeting endogenous FoxO1, FoxO3a and FoxO4 for binding to FoxO DNA binding elements, and, since it lacks a transactivation domain, blocks FoxO DNA binding-dependent transcription.
We also noted that a functional genomic FRT-like sequence should have at least 5 matches in one of its binding elements and at least 6 consecutive matches within both of its binding elements.
The C. elegans transcript annotated as C/D box snoRNA U3 [ 53] also contains an Sm protein binding element and behaves as a typical C/D box snoRNA in the microarray.
The identification of these suppressors provides new insights into the architecture of a functional binding element and its recognition by an important RNA-binding protein.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com