Sentence examples for binding element within the from inspiring English sources
Neither has activity on blunt ended DNA molecules [77], [84] and, therefore, the initial melting of AAV ends may be the function of Rep, which can bind to a Rep binding element within the ITR and unwind the end [85].
These proteins associate to form a variety of homodimers or heterodimers that bind to an AP-1 binding element within the promoter region of inflammatory genes such as COX-2 and MMP-9.
AvrXa7 drives expression of Os-11N3, and AvrXa7 interacts and binds specifically to an effector binding element within the Os-11N3 promoter, supporting the predictive models for TAL (transcription activator-like) effector binding specificity [ 35].
D'Souza, V. et al. Identification of a high affinity nucleocapsid protein binding element within the Moloney murine leukemia virus Psi-RNA packaging signal: implications for genome recognition.
Our investigation into the mechanism underlying the control of CCN2 regulation in fibroblasts has revealed a role for an ETS binding element within the CCN2 promoter.
The mechanism of PrP stabilisation in the presence of manganese does not appear to involve known metal binding elements within the protein.
To determine the presence of putative GATA binding elements within the UP promoters, we analyzed a 2.0 kb fragment upstream from the transcriptional start site of each murine UP promoter sequence in silico using commercially available MatInspector software (Genomatix, Ann Arbor, MI) as previously described [63].
Functional tests reported here reveal that deletion of CTCF binding elements within the MINE does not impact the capacity of this locus to correctly organize an 'accessible' open chromatin domain, suggesting that these sites are not essential for the formation of a competent, transcriptionally active locus.
This comprehensive approach, which we refer to as bandshift scanning, allows for the specific identification of all binding elements within the proximal promoter.
Probes corresponding to the potential binding elements within the MMP12 promoter were generated by PCR using the appropriate biotinylated primers, as follows: −42/+97 (−42 to +97) forward, 5'-GGGAT GATAT CAACT ATGAG TCACT CATAG G-3' and reverse, 5'-TGTAA ACTTC TAAAC GGATC AATTC and3'; and +2/+97 (+2 to +97) forward, 5'-AGAAC CCGGA CTAAG GGC-3' and reverse, 5'-TGTAA ACTTC TAAAC GGATC AATTC AATTC.
