Sentence examples for binding domains which are from inspiring English sources

Our bisulfite sequencing and ChIP-PCR results revealed distinct methylation and chromatin structure boundaries separated by the CTCF binding domains which are located at the 3' end of BLU gene in IMR90 normal cell line (Fig. 5A and 6A).

The aim of the present study was to delineate any possible structural changes in the SARS spike that accompanied receptor-binding, and to precisely localize the receptor binding domains (which are only 14% of the total mass of the spike) within the overall structure, employing cryo-EM and image processing of intact virions bound to soluble ACE2.

These transcription factors are characterized by their DNA binding domains, which are specific to each family.

This strategy is based on simultaneous cell-specific expression of artificial transcriptional enhancers and their unique binding domains which are placed upstream of a weak CSP [ 20, 27, 28].

First, DBD method [ 20] aimed to collect all the proteins containing DNA binding domain, which are sometimes not necessarily involved in the regulation of gene expression, such as transposase, integrase, recombinase, or methyltransferase.

Glycosylation of LDL apo B (the surface protein of LDL) occurs mainly on a positively charged lysine residues within the putative LDL receptor binding domain which are essential for the specific recognition of LDL by the LDL receptor [ 20].

In general, transcription factors functionally result from some important conserved motifs within and outside the DNA binding domain which are related to transcriptional activity, nuclear localization, and protein-protein interactions [ 31].

Another 40 motifs or so have been classified as "non-catalytic" RNA-binding domains, which are often part of multi-subunit RNP complexes [11].

In particular, their catalytic domains and their regulatory DAG-binding domains, which are key for controlling the intracellular localization of these protein kinases, are highly homologous.

NEMO contains two ubiquitin-binding domains, which are essential for the activation of IKK and TBK1 in response to virus infection.

Consistent with a chromatin-associated role, the MORCs display fusions to several DNA- and peptide-binding domains, which are commonly found other eukaryotic chromatin proteins [ 5].