Proteins containing putative DNA-binding domains were detected by means of the HMM library and genome assignments server Superfamily version 1.75 [ 107].
At lower levels of significance, the CBM1 cellulose binding domain was detected as absent from all species in the Pucciniomycotina with the exception of R. glutinis (Table 3, Additional file 16).
A similar observation was noted for Cr VI -stressed S. oneidensis MR-1 Cr VI -stresseda DNA-binding reS.oneidensisator (designated SO2426), also of the OmpR/PhoB subfamily [ 46] of winged-helix DNA-binding domains, was detecellsat the protein level only in chromate-challenged cells [ 26, 27].
A total of 36 TP53 mutations, most commonly in the DNA-binding domain, were detected in 7% of patients.
Evidence of a conserved DNA-binding domain was detected for 51.8% of the wheat sequences identified, i.e. 3,681 sequences (Table 1).
However, the exact role played by these single domain RRs needs further investigation.> While most of Azospirillum RRs with known output domains (64%% ± 1 %) contain a DNA-binding domain (39%% ± 2 %) and may serve as transcriptional regulators, no RNA-binding domain was detected among Azospirillum RRs, suggesting that no control of gene expression through antitermination is mediated by RRs.
Additionally, novel plant specific ZFP-associated domains were detected that may be involved in DNA binding or repressor functions.
A total of 4,160 and 4,135 unique InterPro domains were detected in 46% of C. oncophora and 35.3% of O. ostertagi peptides with the most prevalent domain being 'NAD (P -binding' domain (Table 2).
Frequent re-invention of analogous architectures involving functionally related, but not homologous, domains was detected, such as, fusion of different SMBDs to several types of DNA-binding domains to form diverse transcription regulators in prokaryotes and eukaryotes.
The full-length protein (BiP) and the C-terminal substrate binding domain (SBD) were detected with antiserum that recognizes a C-terminal epitope of hamster BiP, quantified by fluorescence-based immunoblotting on a Licor Odyssey imager and displayed in graphic form in the bottom panel.
