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Genotyping was performed on almost all polymorphisms in the binding domains of three erythrocyte binding antigens (eba175, eba140 and eba181), and repeat sequence polymorphisms ∼2 kb apart in each of three reticulocyte binding homologues (Rh1, Rh2a/b, and Rh4).
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BindingFeature can specify the binding domains of two entities in a complex that are bound to each other.
HSC70 and the subsequently bound HSP90 induce the formation of a deep hydrophobic cleft in the ligand binding domain of GR, required for hormone binding [52], [53], [54].
In all cases the fusion protein is composed of the amino terminal portion of a TET family member that provides a potent transactivating domain and the DNA binding domain of one of several possible ets family members.
This vector is under control of promoter recognized by T7 RNA polymerase and contains a metal binding domain of six histidine residues for use in the affinity purification of the recombinant protein.
Here we show that the membrane-binding domains of two conserved clathrin adaptors, Sla2 and Ent1, co-assemble in a PI 4,5 P2-dependent manner to form organized lattices on membranes.
The binding domains of the three anti-DAF mAbs were identified using yeast surface display technique, and the mimic epitopes of mAb DG3 were screened from a random phage-display nonapeptide library.
The substrate binding domains of the two systems appear to possess different selectivity/affinity for their cognate substrates i.e. ferrated and non-ferrated siderophores.
VEGF-Trap is a reagent which contains the neutralizing binding domains of the two VEGF receptors FLT-1 and KDR, and it is employed as an antiangiogenic therapy in ongoing clinical trials.
Although the clinical success of early molecules was limited, recent data obtained with bispecific T-cell engaging (BiTE) antibodies, which combine the minimal binding domains of the two different antibodies on one polypeptide chain, indicate that such small constructs can indeed have high anti-cancer activity.
A point mutation (hsp90.2-3 hsp90.2-3TP-binding domain of one of the constitutive cytosolic HSP90s, HSP90.2, renders the plant sensitive to pathogens [19].
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