Sentence examples for binding domains of these from inspiring English sources

Human LEF-1 footprinted to the same sites as dTCF as expected from the highly similar DNA binding domains of these proteins [22].

The conserved nucleotide binding domains of these transporters drive transport, whereas the more variable transmembrane domains create the translocation pathway, providing safe passage for a diverse variety of substrates [5].

The high level of sequence variations in the substrate binding domains of these siderophore transporters might be expected due to structural differences of the transported siderophores across various microbial species.

Although the DNA binding domains of these receptors are very similar, the overall degree of homology is low [ 3].

Therefore, neither energy transduction nor conformational changes between the ATPase and the DNA binding domains of these enzymes are directly required for their nucleosome repositioning activity.

Sequence analyses of the RhoA-like GTPases RhoA, RhoB and RhoC as well as of Rac1 failed to detect any mutations within the GTP binding or the effector binding domains of these Rho GTPases.

We have shown previously that it binds the microtubule binding domains of the microtubule-associated proteins, MAP2, MAP4, and tau.

Schlecht et al. recently demonstrated the inhibition of HSP70 and HSC70 (a constantly expressed isozyme of HSP70) using VER-155008, a compound that binds the nucleotide binding domain of these proteins and reduces their ATPase activity (Table 1).

Certain changes to the binding domain of these proteins decrease the binding affinity of these antibiotics and thus confer antibiotic resistance (table 1) (Yoshida et al. 1990).

We used molecular dynamic simulations to determine the specific interactions between NDH and residues within the ligand-binding domains of these two kainate receptor subunits that contribute to the divergent apparent affinities for the compound.

Exploiting differences in the cAMP-binding domains of these proteins, rational drug design has recently been used to synthesize cAMP derivatives that, at appropriate concentrations, selectively activate Epacs or PKA.