Sentence examples for binding domains of many from inspiring English sources

Both are classified as members of the Glycosyl hydrolase domain (GHD) superfamily (Pfam clan CL0369), which contains substrate binding domains of many carbohydrate hydrolases.

Studies have shown, however, that the RNA-binding domains of many ribosomal and nucleolar proteins appear to be coincident with and have the characteristics of nucleolar localization domains [14], [16], [35].

Zinc finger motifs form part of DNA-binding domains of many transcription factors and mediate protein protein interactions (Brayer and Segal 2008).

The commonest hit of ORF117 was with DNA-binding domains of other polypeptides, and many of them were top-ranked using the alignments scores as a sorting criterion.

The usual way to express a conditional version of many proteins is to fuse them to the hormone binding domain of the estrogen receptor.

Further analysis showed that the amino acid Arg145 is highly conserved in many species and is localized in the first actin binding domain of the TNNI3 protein.

The general myosin head-coiled coil-cargo binding domain architecture of many unconventional myosins is designed in such a way that vesicles or organelles are attached at the cargo binding domain of the dimer and the ATPase hydrolysis results in the walking motion of the dimer along the actin filament.

This high conservation in the DNA binding domains suggests that many of the SP/KLF family members bind highly similar DNA sequences.

Given that ligand binding to the ligand-binding domain (LBD) of many nuclear receptors leads to the recruitment of transcriptional cofactors by means of LxxLL motifs, 29 we established a cell-free homogeneous time-resolved fluorescence (HTRF) cofactor recruitment assay for the FXR-LBD.

Synthetic sialic acid derivatives with high affinity proved useful to unravel the biological role of the ligand binding domain, although many of their functions in immunity remain unknown.

Each NCS protein contains four EF-hand Ca2+-binding domains of which 2 3 have the capacity to bind Ca2+, and many are N-terminally myristoylated [2].