Sentence examples for binding domains indicate that from inspiring English sources
The role(s) of its intracellular mammalian ortholog is poorly understood, but a predicted phosphorylation site and a series of Ca2+ binding domains indicate that this protein could be involved in processes determining macrophage activity in immune response [ 76].
Stimulation of elongation is also reduced by a mutation in the Npl3 RNA binding domain, indicating that RNA binding is important.
In vivo studies of colon cancer xenografts expressing a β6-mutant lacking the ERK2 binding domain indicated that deletion of the β6-ERK2 binding motif greatly compromised tumor growth.
This defect was efficiently rescued by expressing Bach1 fragments that lack the DNA binding domain, indicating that its function in mitosis involves a transcription-independent mechanism.
In this study, we showed that 4-HNE could induce nuclear translocation of the NRF2 mutant lacking the KEAP1 binding domain, indicating that 4-HNE may have a direct effect on NRF2 itself.
The predicted specificities on DNA-binding domains indicated that some highly conserved amino acid residues exist across each major group in the tree of land plant life.
Moreover, another pull-down experiment showed that S-labelled NO66 interacted with a segment of Osx (1 270) that contains the transactivation domain but lacks the DNA-binding domain, indicating that this Osx segment was sufficient for NO66 interactions.
Transcripts encoding the pathogenesis-related PR1 and PR2 proteins were elevated in AtGRP7-ox plants but not in plants overexpressing AtGRP7 with a point mutation in the RNA-binding domain, indicating that the regulation involves RNA binding activity of AtGRP7.
The analysis on the 3D structure of CSRP3 zinc-binding domain indicates that this bear-specific amino acid substitution in CSRP3 may have a significant impact on its structure.
