Sentence examples for binding domain would be from inspiring English sources

If not then a global replace with "zinc binding domain" would be appropriate.

B) The claim that the PIP2-Dia interaction is mediated by direct binding through the BD domain would be better substantiated by lipid flotation assays showing that the BD domain binds PIP2 and that the introduced point mutations abrogate binding.

The most obvious explanation for Rab6A binding to the KIF1C motor domain would be to influence KIF1C's microtubule binding and/or motility properties.

An alignment of the mTOR kinase domain with LanC would be essential to underscore if the LanC domain would be compatible for binding.

Invoking eminent domain would be political suicide.

Because the DNA-binding T-domain would be intact, this hypothetical protein could compete with the wild type protein producing a dominant negative effect.

The fact that binding sites for Grb2 and ShcA (and the close Grb2 relative Grap2) are closely associated with EGFR mutation is particularly intriguing, as increased binding of these SH2 domains would be strongly predicted to lead to activation of the RAS signaling pathway via recruitment of the RAS activator Sos [32], [33].

The main difference is that, since RAP has two tight binding sites on cluster II, two such YWTD domains would be needed, one for each binding site.

The T-DNA insert in this line is within the region encoding the S1 RNA binding domain, which would be expected to eliminate the binding ability and function of this protein.

Furthermore, the C terminus of CHMP2B is necessary for binding VPS4 (26, 26); and CHMP2B truncation mutants lose this VPS4 binding domain so would be predicted to fail to dissociate from the endosomal membrane.

By quantitatively assessing expression of a downstream AR target gene, PET tracers targeting PSA subforms or PSMA may identify those patients whose tumors retain AR activity despite blockade of the AR ligand-binding domain and therefore would be ideal candidates for additional therapies to fully inhibit AR signaling.