Sentence examples for binding domain which extends from inspiring English sources
As the p.Pro43_Pro61 deletion is outside the DNA binding domain, which extends from aa119 to aa297, we next assessed whether subcellular localisation or protein stability were affected by the mutation.
Calmodulin dependent protein kinase I (299 320) binding domain, which is a putative CaM-binding region, was obtained from AnaSpec.
Residues 1 150 form the NADPH binding domain, which is a variant of the typical dinucleotide-binding fold.
The IR then undergoes a conformational change in its intracellular β subunits that exposes its ATP-binding domain, which enables ATP binding and autophosphorylation.
This reductase contains 3 domains : a N-terminus RNA-binding domain, a NADPH-binding domain (which positional range coincides with the 13 domains proposed by dissectHMMER in Table 2) and a C-terminus dimerization domain.
The DNA-binding domain is separated by a short hinge region from the ligand-binding domain, which is the largest domain and contains a dimerization domain and a transcription repression domain.
For exploring the lower bound of attainable network lengths, tropomyosin binding, which extends the network, is disabled.
In the "cis" model the N-terminal DID-DD region directly occludes the actin binding surface of the FH2 dimer while in the "trans" model the DID-DD region is maintained at a distance from the surface of the FH2 domain by the long αT helix, which extends from the FH2 domain to present the DAD segment for binding.
Results: We describe DISOPRED3, which extends its predecessor with new modules to predict IDRs and protein-binding sites within them.
This is in agreement with previous studies showing that Src SH3 binding induces major structural changes in Cx43, which extend upstream in the C-terminal domain.
The conservation found in clade 1 eIF4E does not extend to the eIF4G binding domain, in which there are amino acid substitutions within each sub-clade that are likely to have strong affinities for different binding partners.
