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A protein, VC1059, annotated as a short chain dehydrogenase containing an NADPH binding domain, was identified in the active fraction.
A helix-turn-helix motif, the TFIIB recognition element (BRE) binding domain, was identified in every new TFB protein with a sequenced carboxy-terminus [ 31].
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With traditional phage display libraries, mainly the binding domain is identified.
The HA1 domain in which putatively positively selected sites were found was reported, using the alignment of Yang et al. [ 56] in which portions of the influenza HA corresponding to the fusion domain, vestigial esterase domain and receptor binding domain were identified.
In addition, the apicoplast, a nuclear encoded protein with a calcium-binding domain, was identified and localized.
A putative cargo-binding domain was identified in the C-terminal tail of fungal Kinesin heavy chain (KHC).
In addition to the putative peritrophin molecules a transcript with homology to a predicted chitin-binding domain was identified from the clustering of 6 sequences collected primarily from the blood fed Leishmania-infected cDNA library.
The predicted amino acids on S. citri PGK involved in substrate binding domains were identified by searches against the conserved domain databases [27] and are indicated on figure 1A.
Although no known DNA-binding domain is identified in its sequence, VosA contains a nuclear localization signal (NLS -pat7 (241PVKRQRT247) aNLS -pat765.2% likelihood of being locandzed in thasnucleus as predicted by PSORT II (http://psort.nibb.ac.jp).
Cortactin splice variants affecting this F-actin-binding domain were identified not only in mammalians, but also in amphibians, fishes and birds.
The four hypervariable regions in the acceptor-binding domain were identified by multiple sequence alignment of all 91 vertebrate UGT1 variable polypeptides and the corresponding regions of 35 UGT2 proteins in conjunction with analyzing patterns of nt substitutions by the codeml program (see below).
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