Sentence examples for binding domain to be from inspiring English sources

Using fluorescence correlation spectroscopy (FCS) (ref 27), [they] measured the in vivo diffusion constant of LacI-Venus without its DNA binding domain to be D3 = 3 ± 0.3 μm^2/SOM=Supporting Online Materialial).

Previously, we found TP53 mutations affecting the L2/L3 DNA binding domain to be associated with lack of responsiveness to doxorubicin monotherapy [13] as well as mitomycin and 5-fluoro-uracil in concert [14].

We required that the putative transcription factor contain a predictable DNA binding domain to be considered for further analyses.

In both species, repeat 1-to-3 and 4 are on separate exons with in mosquito the 4th repeat of the actin binding domain to be encoded by a single 111 bp large exon 2. Both, sponge (the lowest metazoan) and sea squirt (urochordate) cortactin protein carry 5 repeats.

While monoclonal antibodies require an intact EGFR ligand-binding domain to be active, the RTK inhibitors are active against mutated forms of the EGFR.

Artificial ZFP AZPP) technology allows DNA sequences to be selected directionally and a DNA-binding domain to be designed [ 10- 13].

These substrates can be digested directly by the chitin digestive center of the chitotriosidase and do not need the chitin-binding domain to be involved.

The Ste5 scaffold protein in the pathway was engineered with an artificial leucine zipper-binding domain to be able to recruit a positive or negative pathway modulator to the native signal transduction process.

DNMT1 RFM mutants covering most of the N-terminal regulatory domain of DNMT1 (from the end of the DMAP1 binding domain to BAH1) were generated (Figure 2A).

Both the β-catenin-binding domain and putative DNA binding domain appear to be ancestral domains found in all Xinαs and Xinβs.

Direct binding of the VtrA DNA binding domain to vtrB promoter DNA was then examined by a gel shift assay.