Sentence examples for binding domain that targets from inspiring English sources
Tumor-targeting protein toxins are composed of a toxic enzyme coupled to a specific cell binding domain that targets cancer-associated antigens.
A key feature of Polo kinases is the presence of tandem Polo Box sequences (Pfam PF00659) in the C-terminal nonkinase domain, which like 14-3-3 14-3-3 14-3-3a proteinseptide binding domare that target the kinase to substrates phosphopeptide bindingr kinases [ 100].
The second generation of thrombolytics was produced with the help of genetic engineering, consists of fibrin binding domains that target the activation of plasminogen and thereby fibrin clot degradation.
As control served a similar single-chain antibody, however with a scrambled binding domain, that inhibits specific target binding.
Unlike conventional transcription factors, these proteins do not contain a DNA binding domain that directs them to targets on chromatin; instead, there is accumulating evidence that recruitment and regulation of PcG proteins are coordinated by a number of molecular pathways that act in a combinatorial fashion to repress specific genes in different cell types (Simon and Kingston, 2013).
We describe targeting signals in the N-terminal of DAAM1 (distinct from the Dvl2 binding domain) that allows for targeted protein function.
All 17 BORIS isoproteins contain a ZF DNA binding domain that can mediate recognition of specific DNA targets.
BESS domain is a protein binding domain that can interact each other or with other domains.
Since many BORIS isoproteins possess a ZF DNA binding domain that is highly similar to that of CTCF, their expression in the same cell could interfere with the binding of CTCF to its targets.
Post-transcriptional regulation of both bHLH and Brd E spl -C gE spl -Cmediated by a series of 3' UTR bindingenesaiss that are targeted by mediated 25- 27].
