The G-to-C transition of LOX-1 gene results in the K-to-N change at 167, far from the basic spine arginines of the CTLD domain that represents the ligand binding domain (Figure 6D).
BESS domain is a protein binding domain that can interact each other or with other domains.
This region, which is known as the tail, might therefore represent an alternative cargo-binding domain that could account for some of the KLC-independent functions of KHC.
DnaK has a 45-kDa N-terminal nucleotide-binding domain and a 25-kDa C-terminal substrate-binding domain that are connected by a short peptide linker21.
Zhang, F., Chen, Y. B., Li, M. & Yu, X. C. The oligonucleotide/oligosaccharide-binding fold motif is a poly(ADP-ribose -binding domADP-ribose -bindingNADP-ribose -binding
Loedige, I. et al. The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.
Instead of the derivatisation of albumin with specific sugars, albumin was now modified with cyclic peptide moieties (minimized proteins) that represented the binding domains of cytokines/growth factors responsible for binding to the activated HSC; for example, pentoxifylline is a promising drug that have been benefited from drug targeting strategies [ 7, 135– 135].
We examined amino acids that represent the apical domain of CCTα and could contribute to the substrate-binding site [30].
IrtA, interestingly, has a fused N-terminal substrate binding domain (SBD), representing an atypical subset of ABC transporters, unlike IrtB that harbors only the permease and ATPase domain.
The variable sequence of the eIF4G binding domain represents a strategic point for selection of mRNAs.
