Sentence examples for binding domain that recognizes from inspiring English sources
Among these receptors is VLDLR, which has a binding domain that recognizes VLDL and vitellogenin.
The PPAR α, β, and γ isoforms share a highly conserved DNA binding domain that recognizes specific DNA sequences known as Peroxisome Proliferator Response Elements (PPREs) (11).
Integrins have an extracellular binding domain that recognizes RGD or LVD sequences in ligands such as Fn, fibrinogen, vitronectin, and laminin [ 47, 48].
The WRKY domain is a 60 to 70 amino acid long DNA binding domain that recognizes the W-box (TTGACC/T); however, recent studies suggest this cis-element may be more degenerate and other components are involved for WRKY binding to DNA in response to a specific stimulus [ 30, 31].
An important adjunct to this technology has been the development of a method for pharmacologic control of Cre-mediated recombination by fusing Cre with a mutant estrogen receptor ligand-binding domain that recognizes 4-hydroxytamoxifen (4HT) rather than estrogen [CreER(T); referred to hereafter as CreER; 2,3].
PPARs possess a central DNA-binding domain that recognizes a specific DNA sequence, the PPAR-response element (PPRE), in the promoter regions of their target genes.
Arguably the domain most central to the specific functions of the estrogen receptor family is the conserved DNA-binding domain that recognizes sequences in the responsive genes and dictates with which genes the receptor will interact.
NRs contain a DNA-binding domain that recognizes a specific DNA sequence, as well as a ligand binding domain that renders these factors environmentally-dependent regulators via interaction with distinct cognate ligands [ 4].
ETS is one of the largest transcription factor families and has a highly conserved DNA-binding domain that recognizes a common sequence motif, 5'-(C/A) GGA (A/T) -3' [ 14], which is widely distributed in the PARP1 promoter [ 15].
