Sentence examples for binding domain that is from inspiring English sources

Recent studies have demonstrated that NEMO contains an ubiquitin binding domain that is able to bind to K63-linked polyubiquitin chains on RIP1 12, 12. Another prediction of the model that NEMO restrains RIP1 is that mutations in NEMO that compromise its binding to ubiquitinated RIP1 will also lead to enhanced sensitivity to apoptosis in a NF-κB-independent manner.

Sodium binds at a negatively charged cavity in the extracellular neurotransmitter binding domain that is capped by a small hydrophobic residue.

Glucoamylase produced by amylolytic strains of Saccharomyces cerevisiae (var. diastaticus) lacks a starch binding domain that is present in homologous glucoamylases from Aspergillus niger and other filamentous fungi.

The binding area of IgG to FcRn is located between the CH2 and CH3 domain, distinctly different from the FcγR binding domain that is located between the CH1 and CH2 domain (Kim et al., 1994a; Roopenian & Akilesh, 2007).

However, OREBP lacks the calcineurin binding domain that is present in other NFAT family members and therefore is regarded as a distant relative [11].

The function of calmin is unknown but the protein sequence contains a calponin-like binding domain that is expected to have actin-binding activity [37].

All three pneumoccocal sialidases possess a carbohydrate-binding domain that is predicted to bind sialic acid.

In this study, we show that the Cdom region in the SU from subgroup C feline leukemia virus (FeLV-C) forms a second receptor-binding domain that is distinct from its RBD, and which can independently bind to its host receptor FLVCR1, in the absence of RBD.

Thus, PB1 contains a C-terminal α-helical PB2-binding domain that is essential for nucleotide polymerization activity.

All eukaryotic Pri2 proteins contain a conserved C-terminal iron-sulfur (Fe-S) cluster-binding domain that is critical for primase catalytic activity in vitro.

We present the crystal structure of Bacillus anthracis ThiI in complex with AMP, revealing an extended tripartite architecture in which an N-terminal ferredoxin-like domain (NFLD) connects the C-terminal catalytic PP-loop pyrophosphatase domain with a THUMP domain, an ancient predicted RNA-binding domain that is widespread in all kingdoms of life.