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BESS domain is a protein binding domain that can interact each other or with other domains.
All 17 BORIS isoproteins contain a ZF DNA binding domain that can mediate recognition of specific DNA targets.
Cold inducible RNA binding proteins (CIRBP) are stress proteins with RNA binding domain that can regulate cellular activity under stressful conditions such as hypoxia [ 33] or during brief periods of osmotic stress [ 34] in fish.
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Hsp90 also contains a C-terminal nucleotide-binding domain that can be weakly inhibited with novobiocin.
FOXP3 is a forkhead box transcription factor, containing a DNA-binding domain that can recruit both transcriptional activator and repressor complexes to target genes [ 1].
It encodes a protein with a Myb-like DNA-binding domain that can complement the A. nidulans flbD mutant but has nearly unidentifiable effects on N. crassa conidiation [ 32].
Functional analysis of Htt identified an amphipathic alpha helical membrane-binding domain that can reversibly target it to vesicles and the ER (Atwal and Truant 2008; Atwal et al. 2007).
TFs are special types of proteins that have DNA binding domains that can bind at specific sites of DNA defined by particular sequences of certain length.
The larger isoform has an extended amino terminus that encodes Z-DNA-binding domains that can bind to dsRNA (Oh et al, 2002; Koeris et al, 2005; Placido et al, 2007).
However, the most important criteria for selecting these TF families for analysis was that the gene products contain short, well-conserved DNA-binding domains that can be used to estimate diversity and phylogenetic relationships among family members, and to study gene family evolution [ 44, 47, 53, 55].
Some proteins that bind ATP do so in a characteristic protein fold known as the Rossmann fold, which is a general nucleotide-binding structural domain that can also bind the coenzyme NAD.
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