Sentence examples for binding domain separated by from inspiring English sources
EGI is a two-domain enzyme and is composed of a N-terminal catalytic domain and a C-terminal cellulose binding domain, separated by a linker.
Tandem affinity purification (TAP) strategies include the traditional TAP-tag consisting of a protein A domain and a calmodulin binding domain separated by a tobacco etch virus (TEV) cleavage site.
APOE protein contains two structural domains, the N-terminal receptor-binding domain, and the C-terminal lipid-binding domain, separated by a hinge region ([ 50] for review).
Active Rac1 was then affinity purified with GST-Pak-PBD (Pak 1-p21-binding domain), separated by SDS-PAGE and measured by Western blotting using anti-Rac1 antibodies and total Rac1 protein.
Calmodulin contains two globular EF-hand calcium-binding domains separated by a flexible linker.
The cyclooxygenase active site is located deep inside the catalytic domain separated by a gate from a channel that leads through the membrane-binding domain to the exterior of the protein.
The longer transcript, NRXN1-α, encodes an N-terminal signal peptide with three repeats of two laminin/neurexin/sex hormone-binding globulin (LNS) domains separated by an EGF-like sequence (Fig. 1).
NS5A is an RNA binding phosphorylated protein comprising three domains separated by trypsin-sensitive low complexity sequences (LCS I and LCS II) and an N-terminal amphipathic alpha-helix that anchors the protein to intracellular membranes [ 23- 25].
Even though the seven representative structures of the lysozyme superfamily have no sequence similarity and vary considerably in length, pairwise structure superimpositions showed that they share a common fold, consisting of two domains separated by the binding cleft (Fig. 2) [21] [22].
They are atypical to conventional Rho GTPases in possessing two G-domains separated by two calcium binding EF-hand motifs.
49 The catalytic unit of cathepsin K is arranged in two domains separated by a cleft that contains the substrate binding site.
