Sentence examples for binding domain plays a from inspiring English sources

It is clear that the P-TEFb binding domain of Tat is required for release of P-TEFb from the 7SK snRNP and that the RNA binding domain plays a lesser, but not insignificant role in the release.

It therefore seems unlikely that the THAP DNA binding domain plays a direct role in catalysis in the P-element or Galileo.

Previous studies have suggested that Axin N-terminus (including the RGS domain and the linker region between the RGS domain and the GSK binding domain) plays an inhibitory role in Axin's binding with its partners (Chen et al., 2009; Mao et al., 2001).

Shattering4 (Sh4), a major quantitative trait locus responsible for rice grain shattering, which encodes a transcription factor with an MYB3 DNA binding domain, plays an important role in the establishment of the abscission layer [ 26].

These results suggest that the PP1-binding domain plays a regulatory role in the morphology changing-activities of scapinin.

In contrast, the C-terminal Cos2-binding domain plays a positive role in Smo activity, and its association with Cos2 is stimulated by Hh.

These results indicate that the HSPG binding domain play an important role for VEGF interactions on the surface of the cells.

Structurally, helix 12 of the AF-2 region of the ligand-binding domain plays an important role in the recruitment of coactivators.

Cell wall binding domains play a crucial role in the non-covalent attachment of proteins to cell walls.

Peptide-binding domains play a critical role in regulation of cellular processes by mediating protein interactions involved in signalling.

Strikingly, the non-PtdIns(3) P-binding SGK3(R50A) or SGK3 R90A) mutants displayed only low kinase activity and T-loop and hydrophobic motif phosphorylation, suggesting PtdIns(3) P binding to the PX domain plays a critical role in enabling SGK3 to become phosphorylated at its T-loop and hydrophobic motif and therefore become activated.