Sentence examples for binding domain or the from inspiring English sources

Second, enzymes lacking the tip of the zinc binding domain or the zinc ligands did not antiterminate in response to an intrinsic antiterminator encoded by the put site of phage HK022.

Second, phosphorylation usually occurs in a disordered region of the RNA binding domain or the SRS and stabilizes this region.

Other proteins might proteolyse essential yeast proteins or proteins essential for the system like the DNA binding domain or the activation domain.

Amino acid codon 1170 is located at the carboxydomain of the Her2-neu receptor and is not part of the trastuzumab binding site, the ligand binding domain, or the heterodimerization domain.

The recently reported clear Xlox ortholog in the hydrozoan Turritopsis dohrnii [ 21] does not exhibit either the characteristic PBX binding domain or the similarities in the N-motif of bilaterian Xlox genes.

So locating the DNA binding domain or those key residuals in substrate selection is currently a challenge in this field.

These include missense mutations within the DNA binding domain, substitution mutations that disrupt the nuclear localization signal in the C-terminus, or nonsense and frameshift mutations that truncate the protein within the DNA binding domain or before the nuclear localization signal.

Although some cargoes associate directly with kinesin via the cargo binding domain or via the light chains, others, particularly those expressed in the central nervous system, associate with kinesin adaptor proteins which then bind to the cargo domain to form trafficking complexes (reviewed in [1]).

As predicted, the C1 phage does not discriminate between the GTP-bound form of RhoA, B, C, suggesting that C1 is directed against the GTP binding domain or against the effector-binding domain shared at almost 100% identity among the three proteins.

We examined the effects of DR in animals carrying either the e1368 (class 1) allele mutated in the DAF-2/IR ligand-binding domain, or the e1370 (class 2) allele mutated in the DAF-2/IR kinase domain [17] [19].

On the basis of structural considerations, the β flap, the β′ zinc-binding domain, or the β′ zipper could interact with spacer DNA.