Sentence examples for binding domain of this from inspiring English sources

Analysis of recombinant PM1665 revealed that it is a unique Fn-binding protein in that it binds to the cell binding domain of this glycoprotein, and specifically to the so-called type III (FnIII) domains FnIII9-10 [1].

Clearly, a disulfide bond can and does form between Cys residues substituted into positions 121 or 122 in the nucleotide binding domain and 305 in the carbon substrate binding domain of this NAD-dependent malate dehydrogenase.

Interestingly while neutralizing antibodies to the binding domains of both toxin A and B are moderately protective, enhanced survival is observed when fragments from the glucosyltransferase region of toxin B replace those from the binding domain of this toxin.

Using truncated versions of the cytokinin receptor CRE1/AHK4 in a binding assay, we have experimentally defined the CHASE domain as the ligand binding domain of this class of receptor.

Fine mapping identified the gene underlying this QTL as a Myb transcription factor and association and transformation studies pinpointed the functional nucleotide polymorphism (FNP) to a single base pair within the DNA binding domain of this gene.

The study of the chitin binding domain of this chitinase is of interest since (i) the physiological function of mammalian chitinases remains unknown [ 31] and, more importantly, (ii) the concentration of chitotriosidase, a chitinase expressed in lipid-laden macrophages, is highly elevated in Gaucher disease [ 31– 31].

The P69L mutation affects an amino acid located in the Cdk2 binding domain of the protein (aminoacids 52-93) and this change is predicted with a high degree of confidence to reduce by more than 55% the hydrophobicity of the region (http://www.expasy.org/spdbv/), thereby dramatically altering the environmental conditions necessary for binding to the kinase.

ER: hormone binding domain of the mouse estrogen receptor alpha.

The most abundant of the cassettes with an ascribable function recovered in this study (41 or ∼26% of those with identifiable functions) is one that encodes a homolog to the LysR regulator, or more specifically, the DNA-binding domain of this regulator.

In line with this, a recently identified ARSACS-causing mutation (T3702A) resides in the ubiquitin-binding domain of this protein (Gregianin et al., 2013).

A kinase-dead hppy mutant was made by mutating lysine 55 to glutamic acid in the ATP-binding domain of this kinase using the QuikChange site-directed mutagenesis system (Stratagene, La Jolla, CA, USA).