Sentence examples for binding domain of human from inspiring English sources

Choi, J., Chen, J., Schreiber, S. L. & Clardy, J. Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP.

The crystal structures for two of the identified compounds complexed with the N-terminal ATP binding domain of human Hsp90α were determined.

The authors designed a synthetic peptide of 17 amino acids representing the N-terminus of the putative first ligand binding domain of human VLDLR, this being a unique domain for VLDLR.

X-ray crystal structures of the ligand binding domain of human PXR (hPXR) alone or bound with agonists reveal a highly hydrophobic ligand binding pocket where the aromatic amino acid residue W299 appears to play a critical role in ligand binding.

Here, we modified the binding domain of human SIRPα, the receptor for CD47, for use as a CD47 antagonist.

kHomologue to actin binding domain of human SV1-cortactin.

Within this work, we present optimized protocols for the heterologous overexpression and purification of either the nucleotide binding domain (NBD) or the nucleotide and substrate binding domains of human HSPA9, HSPA8, and HSPA5 in either Escherichia coli or Saccharomyces cerevisiae.

The β-catenin binding domains of human, mouse, chicken, zebrafish, and lamprey Xin were further analyzed with PSIPRED to examine whether the secondary structure is conserved.

We describe mutations in the DNA and ligand binding domains of human PPARγ in lipodystrophic, severe insulin resistance.

52 Briefly, the DNA binding domain of the yeast Gal4 transcription factor was fused in-frame to the N terminus of the ligand binding domains of human PPARα (amino acids 167 469), mouse PPARγ (amino acids 174 476) or human PPARδ (amino acids 139 442) receptors.

This conceptual protein (NeGab; Fig. 1) carries an N-terminal PH domain of the Gab type (PH_GAB) followed by potential recruitment sites for SH3 domains, of which two and three align almost perfectly with the typical and atypical Grb2 binding domains of human Gab proteins, respectively.