Sentence examples for binding domain is situated from inspiring English sources

Moreover, while FokI site is situated in the N-terminal end of the VDR molecule, the ligand binding domain is situated in its C-terminal [41], which explains why FokI and TaqI sites may be playing detrimental roles in the manifestation of T1D in the presence of predisposing MHC alleles.

The ATP-binding site in the N-terminal domain is situated at the base of a deep cleft positioned between two structural lobes.

Conventional kinesin (kinesin-1) dimerizes via an extended stalk domain that forms a coiled coil, so that the two catalytic motor domains are situated at one end of the coiled-coil, while cargo-binding domains are found at the opposite end.

These WW domains are situated downstream of the GUK domain (unlike all other MAGUKs).

The RecQ-type helicase and exonuclease domains are situated in the central and N-terminal regions, respectively.

CHFR binds to PARP-1 via the RAR-binding zinc finger domain, which is situated in the cysteine region of CHFR.

This may be due to a steric hindrance caused by RG27 binding to the SH3 domain, which is situated just between the two SH2 domains that are bound by the Dok-derived peptide (Figure 1A).

Here domain I (NADH binding domain) was used as ankerpoint.

XBP consists of two similar globular domains that are connected by a flexible hinge region, where the d-xylose binding site is situated at the interface between the two domains.

The [4Fe-4S]2+ cluster is bound by residues from the C-terminal α domain and is situated between this domain and the N-terminal β domain.

Mutation of M504 to alanine, an amino acid, which is essential for ligand binding and which is situated in helix 5 of the ligand binding domain, abolishes hormone binding but still allows nuclear localization at only slightly reduced levels in the absence of hormone, whereas nuclear localization of EcRM504R is nearly abolished.