Sentence examples for binding domain is required from inspiring English sources
These data indicate that the PDZ binding domain is required for the disappearance of hCAREx8.
Taken together these results indicate that normal kermit2 function mediated through the PDZ binding domain is required for FN matrix assembly and gastrulation.
Over-expression of E2F1E132 does not promote the phosphorylation of S6K; thereby confirming that the E2F1 DNA binding domain is required for its growth function (Fig. 5A).
Taken together with the results in Figure 7, these data suggest that although the PDZ binding domain is required for the interaction, both the exact sequence of the binding domain and upstream sequences may modulate the interactions of PDZ domain containing proteins.
10.7554/eLife.00205.009 Figure 4. KDM2B ZF-CxxC DNA binding domain is required for CGI binding.
Since the DNA binding domain is required for the effect of MAN1 on the BMAL1 promoter, we next tested whether MAN1 directly binds to the BMAL1 promoter.
These findings indicate that the first nine ZFs of the BORIS DNA binding domain are required for binding to the sixth CTCF target site in the IGF2/H19 ICR in vitro.
However, in that case a large binding domain was required (over 300 aa) and apparently, only one such clone existed in the original library since when a new library was made, overlapping clones were found (22).
