Sentence examples for binding domain is important from inspiring English sources

Recently, our group has demonstrated that Nrf2 acetylation at multiple lysine residues located in the Neh1 DNA binding domain is important in fine-tuning the activity of Nrf2 [30].

The activation or repression domains located outside of the DNA binding domain are important for the regulation of gene expression.

It is likely that the FNR-binding domain is important for some kind of metabolic regulation just in vascular plants, which needs further studies.

The observation of increased ATP hydrolysis relative to nucleosome sliding suggests that the DNA-binding domain is important for efficient conversion of the energy derived from ATP hydrolysis into that required for nucleosome remodelling.

Among these, two lysine residues (Lys324 and Lys333) located at DNA-binding domain are important for transcriptional activation (Fig. 2B) (Giandomenico et al., 2003).

Our data suggest that not only the positively charged amino acid residues (lysine 62, lysine 125 and arginine 130), but also the polar uncharged residues (tyrosine 65 and tyrosine 68) in PTEN's consensus ATP-binding domain are important for ATP binding.

Heparin-binding domains are important molecular structures of FN: one (237 mer) at the N-terminal contains five I-type homologous structures [ 15], and another (272 mer) at the C-terminal contains three type III homologous structures [ 16].

The POZ/BTB domain has been shown to function as a protein-protein interaction domain and the DBD (DNA binding domain) domain is important for sequence recognition and DNA binding activity [ 14].

Strikingly, the Tudor domain of TDRD3 was found to be both required and sufficient for its recruitment to SGs, and the methyl-binding surface in the Tudor domain is important for this process.

The TKB domain is important in binding to a number of molecules, and they then function in signal transduction.

To test more rigorously whether the peptide preceding the DUF1115 domain is important for RNA binding and interaction with the stem II region, we now conducted additional binding experiments by EMSA titrations and ITC (as suggested by Reviewer 3).