Sentence examples for binding domain from the from inspiring English sources

The basis is an inducible chimeric transcription factor, consisting of (i) the ligand binding domain (LBD) of a mutant progesterone receptor that binds the progesterone antagonist RU 486 (mifepristone); (ii) the DNA binding domain from the yeast transcription factor Gal4 (GandDBD); and (iii) the activation domain from the HSV-1 protein VP16 or the human p65 [25].

The R regions of the clf genes have previously been assumed to function as a stalk for the extension of the ligand binding domain from the bacterial cell wall [33].

To detect activation by the glucocorticoid hormone dexamethasone (DEX) we constructed a GFP-based biosensor that reports the level of hormone stimulation in Xenopus cells by fusing the hormone binding domain from the human glucocorticoid receptor (GR) [29] with a nuclear-localizing green fluorescent protein containing a nuclear import sequence (nuc-GFP) [30], [31].

We therefore deleted the LexA binding domain from the recA promoter region.

We were not able to identify the unique binding domain from the sensor protein LuxQ specific for the detection of the AI-2 signal.

In the GeneSwitch™ system, a hybrid regulatory protein containing a DNA binding domain from the yeast GAL4 protein, a truncated ligand binding domain from the human progesterone receptor and an activation domain from the human NF-kB protein is expressed in the pSwitch plasmid.

The three-dimensional architecture of the ribosome binding domain from these IRESes is organized around a core helical scaffold, around which the rest of the RNA molecule folds.

For RolR the structural analysis shows some distinct structural properties of the DNA binding domain from that of known TetRs.

The optimal transactivator conformation was based on DNA binding domains from the chimeric protein ZFHD1 fused to the progesterone receptor ligand binding domain and the NFkb p65 activation domain.

Using the TOUCAN2 program [ 14], the regions were scanned for known binding domains from the Transfac Public v7 vertebrate database.

A comparative modelling approach (SWISSMODEL) using crystallised mammalian c-MYB (1GV2.PDB) as the structural template was conducted in order to study DNA binding domains from the previously selected MYBs.