Sentence examples for binding domain consisting of from inspiring English sources
In contrast, other studies indicated that tBid does not required its N-terminal myristoylation sites to bind to mitochondria, but relies on a CL binding domain, consisting of either helices αH4, αH5 and αH6 [12] or αH6, αH7 and αH8 [23], [24], [24].
As a member of the POU transcription factor family, Oct4 contains a bipartite DNA binding domain consisting of two subdomains connected by a flexible linker of varying length.
All members of the LDL receptor gene family harbor at least one structurally highly similar extracellular ligand binding domain consisting of a series of negatively charged cysteine-rich Ca2+-chelating repeat modules that bind numerous ligands [14].
The C-terminally truncated variant one encoded the NuRD interacting N-terminal domain (BCL11B ΔC-1), the longer variant 2 contained additionally the SUV39H1/HP1/SIRT1/Sp1 /Tat binding domain consisting of the proline-rich region and two central zinc fingers (BCL11B ΔC-2).
The second functional domain in PCNA is the DNA binding domain, consisting of the 4 alpha helices that cluster towards the centre of the trimer and surround the hole into which the DNA fits (Figure 1 blue shaded boxes, and Figure 4).
A DNA binding domain consisting of five zinc fingers is found at its carboxy terminus [ 4, 5].
The C-terminal lipid binding domain consists of a β-sheet of 14 strands and a substrate covering motif on top of the highly hydrophobic substrate binding site.
The client binding domain consists of a long protein loop (the interdomain connecting loop) that connects the two structural domains (Figures 1 and 2) and interacts with client proteins that contain a PCNA interacting protein (PIP) motif (Qxx[M/L/I]xxF[Y/F], where x is any amino acid).
SDS22 encodes a conserved protein whose PP1 binding domain consists of a tandem array of leucine-rich repeats rather than an RVxF motif.
Strikingly, the TALE DNA binding domain consists of tandem 33 35 amino acid repeats, followed by a single half repeat of 20 amino acids.
The DNA binding domain consists of two cysteine-rich zinc finger motifs, two α-helices, and a C-terminal extension, and plays important roles in both nuclear localization and in the interaction with other transcription factors [ 3].
