Sentence examples for binding domain and is from inspiring English sources
TSHZ3 contains one homeobox DNA binding domain and is a potential transcriptional regulator involved in developmental processes [24].
As the cytoplasmic domain of integrins lacks an actin binding domain and is devoid of enzymatic activity, all these effects are mediated by integrin associated molecules.
This negative regulation of HSF-1 is completely dependent on its DNA binding domain and is in contrast to its positive regulation of the FasL gene.
The most abundant form of Tcf1 lacks the β-catenin binding domain and is therefore likely to act as a negative regulator of Wnt signalling.
Domain E, the WGR domain, which is named after the several conserved tryptophan, glycine, and arginine residues it contains, was identified as a potential nucleic acid binding domain and is known to have affinity for PAR polymers.
As the mutated residue is located on the surface of a binding domain and is smaller in size than the wild type it is likely to disturb the external interaction of the domain.
The mutations affected the DNA binding domain and were initially identified as causes of the neurological disorder Rett Syndrome [7].
The human ETS family includes 27 members that share a highly conserved DNA binding domain and are nodal points of various signaling pathways controlling cell proliferation, differentiation and survival [10].
116 (62%) TFs had a DNA binding domain and were enrolled for further analysis.
DELLA proteins lack a DNA binding domain, and are thought to regulate transcription through binding to other proteins, most of which are still unknown.
