Sentence examples for binding domain adjacent to from inspiring English sources

The smallest lattice interaction, covering 150 Å2, brings the anticodon binding domain adjacent to the N-terminus of one monomer in contact with a loop from the active-site domain of a neighboring monomer.

Such peptide insertions into or other mutational manipulations of the heparin binding domain adjacent to VP capsid protein position R588 can abrogate the natural tropism of AAV-2 capsids to heparan sulfate proteoglycane (HSPG -expressing cells and result in de-targeting from tHSPG -expressing [13], [14], [15].

The major class of resistance (R) genes contain a highly conserved nucleotide binding site (NBS) domain adjacent to the N-terminus and a leucine-rich repeat (LRR) domain involved in the host recognition of pathogen-derived elicitors.

The linker domain adjacent to DNA binding maintains an appropriate conformation between the dimerization domain and DNA-binding domain.

In addition to having a CaM binding domain (CBD) in common, each member of the CaMK cascade has a catalytic domain adjacent to a regulatory region containing an autoinhibitory domain (AID) and the CBD [31].

A second calcium-binding site can be inferred to be formed by residues close to the C-terminal end of the catalytic core domain adjacent to the loop which joins the β-barrel 1 domain.

IGFBP-2, -3, -5 and -6 are able to associate with various ECM components and ECM-binding sites can be found within their C-domains adjacent to residues important for IGF binding (Forbes et al, 2012).

Both binding domains are adjacent to predicted coiled-coil segments that allow homo-oligomerization of GIT1 and β-PIX, respectively.

The R72P TP53 SNP in exon 4 lies proximal to the DNA-binding domain and adjacent to the proline-rich, proapoptotic domain of the protein.

The FKBP12-rapamycin binding domain (FRB) is adjacent to the FAT domain and is the site of interaction between mTOR and FKBP12 protein bound to rapamycin [ 11].

Unexpectedly, the sequence Lys-Lys-Phe-Asn at positions 291-294, adjacentothethe CaM binding domain, was found to be sufficient to maintain an inhibited state in a truncated form of the kinase.