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If the head of any agency, in consultation with his or her general counsel, believes that a law that the agency is responsible for enforcing cannot be implemented in constitutional fashion as written, the agency head shall so notify the Attorney General, who shall make a final and binding determination as to how to proceed.
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"The commission has no judicial powers, and it makes no legally binding determinations as to whether unlawful acts have occurred.
For the ligand binding determinations, technical limitations were imposed by the large number of membrane preparations that had to be examined.
The membrane protein:total protein ratio was evaluated from the measures of total tissue protein required for the ChAT assay and of membrane protein required for the ligand binding determinations.
The computational tools are equally useful in combination with experimental-binding determination or in a completely in silico design procedure.
The procedure of polaron binding energy determination is similar to that used in [7].
In addition, their metal complexes are isolated, purity checked by elemental analysis, spectroscopically characterized and their structural analyses were obtained from DFT based calculations including binding energy determination.
The MSCS method allows probing of hot spots, plasticity and hydration simultaneously, providing a powerful complementary strategy to guide computational methods currently in development for binding site determination, ligand docking and design.
These structures of CPT-2 provide insight into the function of residues involved in substrate binding and determination of substrate specificity, thereby facilitating the rational design of antidiabetic drugs.
Ultraviolet visible, Fourier transform-infrared, Raman, Fluorescence and Circular dichroism spectroscopic techniques were applied to study the site of metal ions interaction, binding affinity determination and the effect of metal ions on protein unfolding and HSA conformation.
Alignment of the 13-base asymmetric consensus sequences reveals those positions that are invariant and those that vary and are thus good candidates for discrimination of repressor binding and determination of specificity (Fig. 6C).
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CEO of Professional Science Editing for Scientists @ prosciediting.com