Sentence examples for binding determinants are conserved from inspiring English sources

Compared with the apparent affinity of wild-type IL-13, the affinity drops by factors of 230 and 1300 for IL-13 E11andnd IL-13 R64A, showing that although the affinity of IL-13 for IL-4Rα is 1000-fold lower than that of IL-4 for IL-4Rα, both main binding determinants are conserved.

As such determinants are conserved across protein families, there is a possibility that these are also conserved within families and thus present in the human homolog.

These TRiC binding determinants are disrupted by tumor-causing point mutations that interfere with chaperonin association and lead to misfolding.

The major determinants of ligand binding are conserved between ERα and ERβ consistent with their ability of both to bind oestradiol (Kuiper et al, 1997).

Most of the cation π interactions forming residues in RNA binding proteins are conserved among homologous sequences.

Five aromatic residues involved in the formation of the trimethylated lysine binding pocket are conserved in MRG701CD and MRG1CD.

All nucleotides of the seed sequence of the binding site are conserved in several species, including human, mouse and rat.

SRY binding sites are conserved among human, mouse and rat.

However, not all binding sites are conserved [29].

Several authors confirm that the NP carries multiple antigenic determinants that are conserved among the Coronaviridae [ 33, 34].

Our results strongly suggest that KerV orthologs may be universal virulence determinants since they are conserved in many pathogenic Proteobacteria.