Sentence examples for binding determinant from inspiring English sources

These compounds contain a peptidomimetic binding determinant and a Michael acceptor terminal moiety capable of deactivating the cysteine protease active site.

Peptide arrays further identified a major binding determinant for PKAc was located in exons 5 and 6 of AKIP 1A (Fig. 5A).

The in vitro selected consensus sequence is similar to the natural one, but is extended by an additional binding determinant, a Val, which increases the affinity twentyfold.

This domain facilitates LF entry when it is incubated with B. anthracis PA, which is the cell binding determinant of Anthrax Toxin [30].

Another likely binding determinant, specific to the class C sortases, is a flexible lid that emanates from the N-terminal part of the SrtC enzymes, preceding strand β1, that folds over the active site [34], [35].

The amino acid sequence of VH3-CDR3, thypervariableble region which in most cases acts as a major binding determinant [6] [8], is a unique and distinctive feature of each member of the repository.

Collectively these biochemical and SPOT array experiments indicate that AKAP2 binds directly to the C-terminus of AQP0, in a manner that involves binding determinants between residues 238 and 246 of the channel.

VHL has two well-defined TRiC binding determinants.

This combined approach led to useful insights into the binding determinants of thaperoxides to the malarial enzyme.

Thus, natural molecular evolution as well as combinatorial evolution selected the same α-amylase binding determinants for completely different spatial frameworks.

These structures represent a rare example of an ANL enzyme visualized in both conformations, and also reveal the binding determinants for both CoA and the hydroxycinnamate substrate.