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Thus, at least part of the binding defect associated with the R1699W mutation is likely due to protein destabilization.
The dissociation rates for all Y766A complexes were higher than for the other proteins, reflecting the DNA binding defect associated with Y766A.
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Therefore, based on our data that CUB4 and CUB5 mediate Sog interaction, we tested whether the molecular defect associated with these mutant Tld proteins is reduced binding to Sog.
This defect may represent the result of a sinus venosus defect associated with cor triatriatum.
Oxidative phosphorylation defect associated with primary adrenal insufficiency.
Microcephaly is considered the most severe birth defect associated with Zika.
Simhadri, S. et al. Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Mangin, P. et al. Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency.
Microcephaly is the most devastating birth defect associated with ZIKV-infected newborns.
Colombia has confirmed the first two cases of a rare birth defect associated with the spread of Zika.
Therefore, the stress related competitive defect associated with the constitutive activation of PrfA appears distinct from the defect associated with the loss of SigB function.
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