Sentence examples for binding data show that from inspiring English sources
Strikingly, even though in vivo (Cho et al., 2012; Hafner et al., 2013; Wilbert et al., 2012) and in vitro (Towbin et al., 2013) binding data show that Lin28a binds many more pre-miRNAs, only some members from the pre-let-7 family are efficiently uridylated.
Supporting this, comparisons against all ENCODE TF binding data show that for HNF4A, CEBPA, and FOXA1 singletons, the top ChIP-seq peak association in HepG2 cells corresponded to the TF assayed.
Our binding data show that binding of H3K4me3 to PHD3 and binding of the CYP33 RRM domain to PHD3 are mutually inhibitory, implying that PHD3 is a molecular switch for the transition between activation and repression of target genes.
In line with previous studies [ 17], the binding data show that Phe265 is important for anchoring the peptide in the HLA-DR pocket; all peptides truncated beyond Phe265 (266–275 and 267 275) showed strongly reduced affinities (IC50 values > 100 μM).
Binding data show that, in general, compounds 2 34 bind to the AMPA receptor with good affinity and selectivity.
Consistent with our binding data showing that the Arg SH3 domain binds N-WASp, we find that the Arg SH3 domain also activates N-WASp to promote actin polymerization by the Arp2/3 complex.
The in vitro binding data showed that the (S -isomer of II waS -isomerin the bradykinin B2 receptof-bIIding assay wash a Ki of 33 nM.
In vitro binding data showed that, compared to the original mAbs, the modified mAbs (S-mAbs) had greater capability of binding two TNF molecules simultaneously.
Analysis of the binding data shows that mAbs directed at epitopes in the V3, C5 and gp41 Cluster I region bound best to the viruses examined, suggesting that these are the regions most exposed and conserved on intact, native HIV-1 virions of different clades.
The regression coefficients of the PLS-model based on DR4 binding data showed that four of the seven amino acids introduced in p263 were well tolerated (lower part of Figure 6).
