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Virus binding could be blocked with unlabeled M. amurensis lectin.
LDL receptor binding could be blocked and up- or down-regulated.
Moreover, initial human studies have shown that [I]ADAM binding could be blocked by selective serotonin reuptake inhibitors (SSRIs).
This is consistent with MD simulations indicating that substrate or inhibitor binding could be blocked by the bulky R180 side chain.
Binding could be blocked by predosing with ETAR antagonist atrasentan, proving specificity.
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This binding process could be blocked by VP2 antibody, and the blocking capability was directly proportional to the dosages of VP2 antibody and 3(d)).
The Cy5.5-conjugated peptides bound mainly to the cell surface with high binding affinities and could be blocked by free cMBP.
Thus, only two compounds might be sufficient to block most noroviruses in the two genogroups studied here, each group sharing a similar binding interface that could be blocked by one common inhibitor.
Although BP1, BP2, and BP3 all bound to BCG-specific γδ T cells, only the binding of BP3 could be blocked by functional γδ TCR blocking monoclonal antibody (Figure 3B).
Accordingly, receptor binding and activation could be blocked by TRAIL-R2-neutralizing monovalent Fab fragments.
Using c−RGD (10 μg ml−1), binding to gelatin could be blocked completely, with no difference in the response to EDTA-inhibited samples or BSA controls.
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