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Moreover, the increase in surface AMPA binding correlates with an increase in the amounts of GluR subunits localized to the PSD fraction, without changing the total abundance of GluRs.
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Conversely, the loss of NF-Y binding correlates with a decrease of acetylated histones, the recruitment of HDAC1, and a repressed heterochromatic state with enrichment of histones carrying modifications known to mediate silencing of gene expression (H3K9me3, H3K27me2 and H4K20me3).
These docking calculations coupled with HINT interaction analyses are able to represent the complex structures and the binding modes of inhibitors such that calculated and measured free energies of binding correlate with an r2 of 0.76.
In spermatocytes HSF1 binding correlates with transcriptional repression on a large scale.
It is not known how exactly antibody binding correlates with variable glycosylation or oligomerisation in a functional or structural sense, and further investigation is required.
We and others, have previously reported that the HAT p300 enzyme binds NF-Y target promoters, and that its binding correlates with the presence of highly acetylated histones.
We demonstrate that CTCF-mediated chromatin loops between promoters and intragenic regions are prevalent and that when exons are in physical proximity with their promoters, CTCF binding correlates with exon inclusion in spliced mRNA.
Toxicity depends on metabolic activation, and reactive metabolite binding correlates with tissue and site susceptibility.
The pace of binding correlates with carrier avidity, concentration, perfusion rate, and the density of binding sites.
Future studies will address why positive-cooperative metal binding correlates with the abilty to protonate the anionic intermediate.
Next, we were interested in expression levels of Tip60 enriched genes and how Tip60 binding correlates with gene expression.
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