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Using the constants determined from these studies and release studies conducted at varying pH, permeability coefficients and membrane binding constants for each species of TPT were determined.
(E ) Summary of kinetic and thermodynamic binding constants for each class of binding event.
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Isothermal titration calorimetry experiments were used to acquire binding constants for the inhibitor MP265 and nucleotides that bind to the active site of ΔCcMreBdh.
This reparameterization shows that the two variant assumptions on the Ca2+ binding to the uniporter (Case 1 and Case 2) are indistinguishable from each other, indicating that the external and internal Ca2+ binding constants for the uniporter may be equal (Case 1).
Equilibrium binding constants for the axial coordination of inorganic anions were determined by cyclic voltammetry measurements.
The equilibrium binding constants for DB244 are 10-20 times greater than that for DB226.
The synthetic alkylamine-modified CD derivatives had higher equilibrium binding constants for binding with AHL than the native CDs did, consistent with the improved QS inhibition.
A strong NADH binding in contrast to weaker NAD+ binding of the protein was inferred from fluorometrically determined binding constants for the dinucleotide cofactor.
Extraction of microscopic binding constants for the linked equilibrium between anion and proton binding indicates that anion selectivity by YFP is related to hydration forces.
The spectroscopic data indicated the binding constants for polyphenol complexes with β-Lg in phosphate buffer pH 7.4 to be in the order of MeG > EGCG > EGC.
Recent progress in super-computing, coupled to theoretical insights, allows the calculation of the Gibbs free energy, and therefore accurate binding constants, for usually large ligand receptor systems.
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