Sentence examples for binding complex that was from inspiring English sources

This cellular response is controlled by the hypoxia-inducible factor (HIF) family of transcription factors, a DNA binding complex that was first defined as a regulator of erythropoietin (Epo) gene (EPO) expression but which is now known to be conserved in all animal species, irrespective of the presence of specialised oxygen transfer systems such as the lungs, heart, and blood (Semenza, 2004).

ADAM22 resides in a complex with NgR1 and facilitates LGI1 binding to this receptor, suggesting that NgR1 and ADAM22 collaborate to create an LGI1 binding complex that is important for synapse formation (Thomas et al., 2010).

One intriguing possibility is that genes that need to be rapidly responsive to physiological signals require Runx-DNA binding complexes that are less stable and/or have shorter half lives.

The linear dependence of the reaction with [NO] combined with small observed second-order rate constants (kobsNO, Fe3+ in Table 1) is indicative of a bimolecular association rate constant for binding to the pentacoordinate complex that is much slower than the rate constants for His binding and dissociation [22].

SNPs may change transcription binding affinity of the BMAL1/CLOCK complex that is necessary for expression of the target genes.

This second type of binding results in a MAC HGD complex that is stable upon exhaustive dialysis.

Alizarin red detects the presence of calcific deposition within the matrix by binding calcium ions to form a complex that is intensely red.

Degradation of HIF-1α protein is mediated by the VHL tumor-suppressor protein, which interacts with von Hippel-Lindau binding protein 1 (VBP1) and forms a complex that is transported to the nucleus or cytoplasm.

Upon exposure to DNA-damaging agents, the NcRNA CCND1 binds the RNA-binding protein TLS to form a ribonucleoprotein complex that is recruited to the CCND1 promoter and inhibits transcription [ 119].

GABAA gamma2 is one subunit of GABAA receptor complex that is involved in binding of GABAA receptor modulators such as benzodiazepines [57]; it is a representative of GABA system genes.

BindingFeature can specify the binding domains of two entities in a complex that are bound to each other.