Sentence examples for binding complement from inspiring English sources

To map regions within VCP involved in binding complement and heparin experimentally, surface plasmon resonance (SPR) and recombinantly expressed VCP (rVCP) constructs were employed.

Chicken antibodies (immunoglobulin Y; IgY) to the alpha Gal epitope (galactose alpha-1,3-galactose) bind to alpha Gal antigens of mouse and porcine tissues and endothelial cells in vitro and block human anti-alpha Gal antibody binding, complement activation and antibody-dependent cell-mediated lysis mechanisms.

Therefore, other O. anthropi surface molecules, such as capsule polysaccharides, may be responsible for binding complement.

For example, human pathogenic fungi Aspergillus fumigatus and Candida albicans evade immune attack by binding complement regulators in order to suppress complement effector molecules [31].

Further support for the role of the condensed nature of heterochromatin or its specific epigenetic and protein binding complement in preventing H2AX phosphorylation following IR comes from the use of histone deacetylase inhibitors.

Paramyosins, which are multifunctional modulators of the host immune response, play a role in binding complement components, immunoglobulins, and secreted components of cellular immune response [ 31– 31].

Many more, however, could be capable of binding complements with their own composition.

Erythrocyte CR1, a C3b/C4b-binding complement-regulatory protein, is sensitive to proteolysis in vitro.

However, the binding of complement proteins is independent of complement activation, and inhibition of complement at the stage of C1q or C3 does not affect the binding of the complement components.

We hypothesized that C7 treatment of UPEC K1 would result in increased binding by complement C3, initiating recruitment of the complement attack complex.

PTX3 released in response to microbial recognition can bind specific pathogens such as fungi, bacteria and viruses, promoting phagocytosis and subsequent clearance of the pathogen via its binding to complement component C1q to induce classical complement activation [3], [5], [6].