Sentence examples for binding competence of from inspiring English sources

Native ESI MS also allowed the receptor binding competence of Tf loaded with non-ferric metals to be evaluated.

Upon addiction of micromolar amounts of Zn2+, the protein undergoes a refolding to the native form and reacquires DNA-binding competence [ 56].Trying to investigate the cause of this alteration we found that the exposure to nanomolar concentrations of the beta-amyloid peptide 1-40 (Aβ 1-40) induced the expression of the unfolded p53 protein isoform in fibroblasts derived from non-AD subjects [ 3].

These truncated forms lack DNA-binding domains, but retain T3-binding competence [ 39].

This demonstrates the competence of the binding and translocation domains of PE to mediate delivery of the DTA and RTA catalytic domains into cells cytoplasm and, importantly, that NS3 cleavage mediated enhancement in the enzymatic activity of the two zymoxins (as was detected by in-vitro assays) is practically translated to enhancement in cytotoxic activity.

It is not surprising because the DNA-binding ability and the transactivation competence of HSF1 are regulated independently.

To understand how Hox operate in vivo, we mapped Meis, Pbx, and Hoxa2 binding in the native area of competence of Hoxa2, the IIBA.

We conclude that the insertion of W333 into the hydrophobic pocket of the Fz receptor, as a critical binding event in the Wnt CTD, might well be independent of the signaling competence of the ligand-receptor complex.

All these allow MdOS to mask entrance of ATP-binding pocket, thereby blocking the engagement of ATP with VEGFR2 and EGFR, which further help understand the ATP-competitive inhibitory competence of MdOS.

Signaling is not just one competence of many but rather the essential competence of cells.

Competence guidelines include flow charts to assess the competence of prehospital and emergency department teams.

The non-binding opinion adds that the plan "infringes upon the taxing competences of non-participating member states", making it incompatible with the EU treaty.