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The determination of the complex structures of avelumab and BMS-936559 with PD-L1 has enabled us to compare the binding characteristics of these MAbs to elucidate the rules of interaction between therapeutic MAbs and PD-L1 (Lee et al., 2016; Liu et al., 2017).
The elucidation of the binding characteristics of these TFs is one of the obvious follow-up questions.
The binding characteristics of these phage antibodies provide useful information regarding the conformational relatedness of the AP isozymes and thus could also serve as structural probes.
Such a difference in FaDu tumor response to panitumumab and cetuximab may be due to the difference in the binding characteristics of these therapeutic antibodies to EGFR.
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On the other hand, it is possible that the structural differences between eu- and heterochromatin at the molecular level might have influenced the binding characteristics of the dyes so that these differences at a molecular scale are now, again, present in the scaling window of light microscopic observation.
The absence of these two amino acid residues most probably affects the binding characteristics of the second protein variant.
The results indicate that the binding characteristics of the prototype adsorbent are similar to those obtained with Protein G Sepharose.
The DNA binding characteristics of the carboxamides were evaluated by thermal denaturation experiments and by ethidium bromide displacement assay.
In addition, we further define the binding characteristics of the cognate ligands for each group of PTB domains.
The binding characteristics of the reagents used in an immunoassay determine the assay response to the analyte concentrations.
The binding characteristics of the imprinted membrane GMIM, the permeability and separation property for matrine were investigated in depth.
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