Sentence examples for binding characteristics of human from inspiring English sources

In this study, we compare binding characteristics of human IgG subclasses commonly used in drug development (IgG1, IgG2, IgG4) and their respective Fc silent versions (IgG1σ, IgG2σ, IgG4 PAA) to human, mouse, and cynomolgus monkey Fcγ receptors.

To evaluate the resulting scenarios of vertebrate globin evolution, and to identify important, evolutionary conserved protein structure and ligand binding characteristics of human Ngb and Cygb, it is mandatory to identify and study candidate globin orthologs in non-vertebrate taxa.

Both these novel interaction sites may alter the binding characteristics of human PCDH11X through the formation of disulfide bonds, a mechanism previously described (Chen et al. 2007) for the Xenopus δ2-family member paraxial protocadherin, and γ-Pcdh-A3 tetramers (Schreiner and Weiner 2010).

In the study shown here, we evaluated the binding characteristics of a human monoclonal Fab (named e20) that was able to bind E2 glycoproteins of all tested genotypes.

To provide proof of concept of our glycosphere assay, we tested the binding characteristics of two human-adapted and two avian-adapted hemagglutinins whose glycan-binding characteristics have been studied in detail.

Here, we use HAE cultures and tissue sections of human tracheal epithelium to determine the binding characteristics of wild-type and select mutations of H5 HA to human airway epithelium.

The mechanism of RDX seizure induction revealed in the present study in rats is probably similar in humans, because the binding characteristics of TBPS to the GABAA receptor are similar in rat and human brain (Atack et al. 2007; Cole et al. 1984).

Thus, the treatment with AN-215 did not affect the binding characteristics of receptors for BN/GRP in U-87MG human glioblastoma.

The tumor-associated binding characteristics of this antibody, its efficient internalization, and its human nature, make PH1-IgG1 a valuable candidate for further studies as a cancer-targeting immunotherapeutic.

Therefore we generated human single chain and diabody antibody derivatives based on the binding characteristics of the murine monoclonal antibody Guy's 13.

The first X-ray crystallography structures published of a human HDAC, HDAC8, provided valuable insights into the catalytic mechanism and binding characteristics of various inhibitors.