Sentence examples for binding characteristics as the from inspiring English sources

Here we have used precise information regarding the functional recognition sequence (epitope) of a rabbit polyclonal antibody with attractive binding characteristics as the basis for generation of a renewable mouse monoclonal antibody.

To determine if Bs20x22 maintained similar binding characteristics as the parent mAbs, Ramos cells (CD20/CD22 positive) and 293T cells transfected with either CD20 or CD22 were stained with Bs20x22, rituximab, or HB22.7.

Animals received one of the following antibodies by intraperitoneal injection: 6G1, which is pan-amyloid-β specific and has similar binding characteristics as the diagnostic 6E10 antibody (Barghorn et al., 2005); A-887755, a globulomer-derived antibody which specifically detects oligomeric, but not monomeric or fibrillar amyloid-β (Hillen et al., 2010); IgG2a as a non-amyloid specific control.

Notably, even such fundamental binding characteristics as the equilibrium dissociation constant (Kd) between Nups and NTRs are still matter of discussion - estimates range from a few nM to several mM (Bednenko et al., 2003; Ben-Efraim and Gerace, 2001; Tetenbaum-Novatt et al., 2012; Tu et al., 2013).

The binding characteristics as well as the size and morphology of the MIPs were examined.

Several factors influence dopamine (DA) and serotonin (5-HT) transmission, particularly, the reuptake transporters, which remove the transmitter substances from the synaptic cleft, the number of receptors and their binding characteristics, as well as agents that regulate the catabolism of monoamines.

These interpretations assume that each of these sequences used to replace the tDNA have the same in vivo binding characteristics at the ATG31 locus as they do in their native chromosomal locations.

As detailed in Figure S3, despite the very distinct functionalities of the different NTRs, the smFRET and FCS measurements of the different Nups and NTRs indicate similar binding characteristics as for the Nup153FG⋅Importinβ complex.

MAb 139H2 was compared with MAbs OC125 and OV-TL 3, all reactive with ovarian carcinomas, for the binding characteristics as IgG and F ab' 2 fragments with the use of the OVCAR-3 cell line grown in vitro and as s.c. xenografts.

The focus of this study was on the molecular interactions, dynamics and binding characteristics as evaluated by a battery of experimental techniques.

Cdc45 and PCNA also displayed differential chromatin binding characteristics as CHO progress into S-phase, but unlike that for MK cells, both proteins became chromatin-bound at the G1-S transition rather than in late-G1 (Figure 4A, chromatin fraction).