Sentence examples for binding changes in both from inspiring English sources

To evaluate the pH dependent variations in binding, changes in both the ligand and in the enzyme had to be taken into account.

However, this mutational scheme failed to induce significant binding changes in the already-high-affinity C225 Fab/huEGFR interface.

Recent advances in robotic fluid handling make it possible to perform automated high throughput experiments including fast screening of solution conditions, measurement of structural responses to ligand binding, changes in temperature or chemical modifications.

However, only ~0.7% (172) genes displayed significant Pol II binding changes in E2-treated antiestrogen-resistant cells.

Leaks to German newspapers and news agencies suggest that Berlin is moving swiftly to complete proposals for a binding change in repayment terms in the event of default.

These steric clashes are relieved as a result of GppNHp binding and structural changes in both proteins.

This binding event induces conformational changes in both the polymerase and the primer template DNA, which lead to assembly of an active site with the geometry required for catalysis.

Manipulation of the (distal) heme cavity architecture is often reflected by changes in both binding rates as well as in the strength of binding of cyanide to the ferric heme iron.

The lack of PDE10A binding change observed in our initial data may be explained by the short time period between D-amphetamine treatment and the PDE10A microPET determination.

GTP binding is accompanied by conformational changes in both RF3 and the ribosome (Gao et al., 2007).

An excess of Trp could occur in PE because of increased placental amino acid transport [ 92] (though Trp was not measured in the latter study) or if Trp release from albumin-binding sites is enhanced through changes in both [albumin] and [NEFA] beyond those observed in normal pregnancy, leading to increased flux down the KP.