Sentence examples for binding change observed in from inspiring English sources

The lack of PDE10A binding change observed in our initial data may be explained by the short time period between D-amphetamine treatment and the PDE10A microPET determination.

There was no change observed in the binding energies corresponding to the manganese and nickel after the reaction indicating that there is no change in oxidation state of the metals.

The high [DNA]/[compound] ratio needed for total binding, together with the negligible changes observed in absorption spectra (not shown), point to a weak interaction of these molecules with the nucleic acid.

This tissue specificity was reinforced by recent observations demonstrating that deletion of p62, a ubiquitin and LC3/Atg8 binding protein, rescues the pathological changes observed in autophagy deficient liver but does not appear to alter the phenotypic changes seen following deletion of Atg7 in the brain [ 15].

Thus, the anti-autophagic activity of Bcl-2 was not verified as the mild changes observed in the binding and sequestration of Beclin-1 by Bcl-2 were not expected to disturb the formation of the class III PI3-kinase complex that is critical to the induction of autophagy.

In other words, the binding site is more deterministic than expression changes observed in microarray analysis.

The favorable entropic changes observed in cooperative oxygen binding in HbI will have contributions from both protein conformational entropy and solvent entropy.

The same intuition that allows us to construct position weight matrices (i.e., that we may average over all the binding sites to learn the average sequence specificity) allows us to compute the rate of evolution across the motif by averaging the changes observed in the individual binding sites.

Taken together, these conformational changes observed in the BoNT/A LC protease upon binding with different inhibitors reveal a highly 'plastic' binding cleft.

Conformational changes observed in these domains on DNA binding suggest that they transduce DNA-induced conformational changes to the catalytic core and regulate kinase activity.

Compared with adding A-ASOR alone, the binding of ASOR to cells was significantly reduced in the presence of sASGPR in the medium, while no change of ASOR binding was observed in the presence of BSA.